主な論文 |
- A new method for the preparation of a calcium activated neutral protease highly sensitive to calcium ions. Biochem Biophys Res Commun. 100:1189-1194,1981.
- Limited autolysis of calcium-activated neutral protease changes its sensitivity to calcium ions. J.Biochem. 90:275-278, 1981.
- Autolysis of calcium-activated neutral protease of chicken skeletal muscle. J.Biochem. 90:1787-1793, 1981.
- Comparison of two forms of low calcium-requiring protease. Biomed.Res. 3:699-702, 1982.
- A new simple enzymatic assay method for urinary polyamines in humans. Cancer Res. 43:2363-2367, 1983.
- Purification of a calcium-activated neutral protease from human placenta. Biochim.Biophys.Acta 802:379-383, 1984.
- Urinary polyamines as a tumor marker. Cancer Detection and Prevention 8:189-192, 1985.
- Urinary polyamines as a marker of response in cancer treatment. Recent Prog. in Polyamine Res. 8:459-468, 1985.
- The value of urinary polyamine assay in stomach cancer: comparison with serum carcinoembryonic antigen. Cancer 56:1630-1635, 1985.
- Polyamines. Methods of Enzymatic Analysis 8:566-572, 1985.
- Purification and characterization of high calcium-requiring neutral proteases from porcine and bovine brains. Biochemistry 25:8396-8402, 1986.
- Effects of DL-alpha-difluoromethyl- ornithine on the growth and metastasis of B16 melanoma in vivo. Int. J. Cancer 39:244-247, 1987.
- Epidermal growth factor expression in the congenital polycystic mouse kidney. Kidney Int. 39:57-62, 1991.
- Transforming growth factor-β suppresses the invasiveness of human fibrosarcoma cells in vitro by increasing expression of tissue inhibitor of metalloprotease. Biochem.Biophys.Res.Commun. 176:129-136, 1991.
- Synergistic antiproliferative activity of human fibroblast interferon in combination with alpha-difluoro-methylornithine against human gastric cancer cells in vitro. Cancer 69:2395-2399, 1992.
- Signaling site of laminin with mitogenic activity. J.Biol.Chem. 267:4285-4288, 1992.
- Induction of a 92 kDa typeIV collagenase/gelatinase by invasive human fibrosarcoma genomic DNA transfection leads to an invasive phenotype. Biochem.Biophys.Res.Commun. 181:1539-1547, 1992.
- Identification of new mutations in sterol 27-hydroxylase gene in Japanese patients with cerebrotendinous xanthomatosis (CTX). J.Lipid Res. 35:1031-1039, 1994.
- Ornithine decarboxylase is directly involved in mouse mammary carcinoma cell invasion through reconstituted basement membrane (matrigel). Biochem.Biophys.Res.Commun. 208:1106-1115, 1995.
- Tumor Necrosis Factor Alpha- and lymphotoxin stimulate human myeloblastic leukemia cell (ML-1) invasion through a reconstituted basement membrane (matrigel) with concomitant induction of 92kDa gelatinase secretion. Cancer Lett. 98:233-240, 1996.
- Genetic analysis of a Japanese cerebrotendinous xanthomatosis family: identification of a novel mutation in the adrenodoxin binding region of the CYP27 gene. Biochim.Biophys.Acta 1317:119-126, 1996.
- Molecular cloning and expression of a rabbit sterol 12-hydroxylase. J. Biol. Chem. 271:32269-32275, 1996.
- PET analysis of a case of cerebrotendinous xanthomatosis presenting hemiparkinsonism. J.Neurol.Sci. 138: 145-149, 1996.
- Anti-α3 integrin antibody induces the activated form of matrix metalloprotease-2 (MMP-2) with concomitant stimulation ofinvasion through matrigel by human rhabdomyosarcoma cells. Int.J.Cancer 70:106-111, 1997.
- Ornithine decarboxylase overexpression in mouse 10T1/2 fibroblasts: Cellular transformation and invasion. J.Natl.Cancer Inst. 89:567-571, 1997.
- Novel homozygous and compound heterozygous mutations of sterol 27-hydroxylase gene (CYP27) cause cerebrotendinous xanthomatosis in three Japanese patients from two unrelated families. J.Lipid Res. 38:870-879, 1997.
- Alternative pre-mRNA splicing of the sterol 27-hydroxylase gene (CYP27) caused by a "G" to "A" mutation at the last nucleotide of exon 6 in a patient with cerebrotendinous xanthomatosis (CTX). J.Lipid Res. 39: 509-517, 1998.
- Silent nucleotide substitution in the sterol 27 hydroxylase gene (CYP27) leads to alternative pre-mRNA splicing by activating a cryptic 5' splice site at the mutant codon in cerebrotendinous xanthomatosis patients. Biochemistry 37:4420-4428, 1998.
- Genetic analysis enables definite and rapid diagnosis of cerebrotendinous xanthomatosis Neurology 51:865-867, 1998.
- A novel Arg362Ser mutation in the sterol 27 hydroxylase gene (CYP27); its effects on pre-mRNA splicing, and enzyme activity. Biochemistry 37:15050-15056, 1998.
- Ornithine decarboxylase and cancer. Cancer J. 11:294-297, 1998.
- Cholestanol induces apoptosis of cerebellar neuronal cells. Biochem.Biophys.Res.Commun. 256:198-203, 1999.
- Human rhabdomyosarcoma cells retain insulin-regulated glucose transport activity through glucose transporter 1. Arch.Biochim.Biophys. 373: 72-82, 2000.
- Cholestanol induces apoptosis of corneal endothelial and lens epithelial cells. Invest.Ophthalmol.Vis.Sci. 41:991-997, 2000.
- Convenient method for analyzing differential expressing gene in the plural cells. Bioimages 8:91-96, 2000.
- Overexpression of vacuolar ATPase 16 kDa subunit in 10T1/2 fibroblasts enhances invasion with concomitant induction of matrix metalloproteinase-2. Biochem.Biophys.Res.Commun. 278:390-394, 2000.
- Formation of hydroxy radicals by environmental estrogen-like chemicals in rat striatum. Neurosci.Lett. 296:41-44, 2000.
- Effects of para-nonylphenol on 92kDa gelatinase secretion by human peripheral lymphocytes and U937 cells in vitro. Biochem.Biophys.Res.Commun. 279:270-274, 2000.
- p53 independent G1 arrest induced by DL-a-difluoromethylornithine. Biochem.Biophys.Res.Commun. 280: 848-854, 2001.
- Genetic analysis of phytosterolemia. J.Inherit.Metab.Dis. 24:43-50, 2001.
- Anti-alpha integrin antibody induces secretion and activation of 72 kDa progelatinase by human fibroblasts. Biochem.Mol.Biol.Int. 51: 1-7, 2001.
- Histamine increases interstitial adenosine concentration via activation of ecto-5'-nucleotidase in rat hearts in vivo. J. Pharmacol. Exp.Ther. 298: 1-6, 2001.
- Calreticulin is directly involved in anti-α3 integrin antibody-mediated secretion and activation of matrix metalloprotease-2. Biochem.Biophys.Res. Commun. 283: 297-302, 2001.
- Frontal lobe dementia with abnormal cholesterol metabolism and heterozygous mutation in sterol 27-hydroxylase gene (CYP27). J.Inherit.Metab.Dis. 24: 379-392, 2001.
- Protective effect of tamoxifen on 1-methyl-4-phenylpyridine-induced hydroxyl radical generation in the rat striatum. Neurosci.Lett. 308:87-90, 2001.
- Allopurinol suppresses paranonylphenol and 1-methyl-4-phenylpyridinium ion-induced hydroxyl radical generation in rat striatum. Neurosci.Lett. 306 :9-12, 2001.
- Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer. Biochem. Biophys.Res.Commun. 288:212-216, 2001.
- Protective effect of histidine on para-nonylphenol enhanced hydroxyl free radical generation induced by 1-methyl-4-phenylpyridinium ion (MPP+) in rat striatum. Biochim.Biophys.Acta 1568:171-175, 2001.
- Antisense oligonucleotides targetted to midkine, a heparin-binding growth factor, suppresses tumorigenicity of mouse rectal carcinoma cells. Cancer Res. 61:8486-8491, 2001
- Overexpression of ornithine decarboxylase enhances endothelial proliferation by suppressing endostatin expression. Blood 99:1478-1481, 2002.
- 5'-, 3'-Inverted-thymidine-modified antisense oligodeoxynucleotide targeting midkine: its design and application for cancer therapy. J.Biol.Chem. 277:23800-23806, 2002.
- Coexpression of glucose transporter 1 and matrix metalloproteinase-2 in human cancers. J. Natl. Cancer Inst. 94:1080-1091, 2002.
- Determining the levels of matrix metalloproteinase-9 in portal and peripheral blood is useful for predicting liver metastasis of colorectal cancer. Jpn. J. Clin. Oncol. 33: 186-191, 2003.
- Enhanced susceptibility of LDL to oxidativemodification in a CTX patient: role of chenodeoxycholic acid in xanthoma formation. J Atheroscler Thromb. 11:167-172, 2004.
- In utero and lactational exposure to 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD) affects tooth development in Rhesus monkeys. Reproductive Toxicology 20: 21-30, 2005.
- Ornithine decarboxylase, mitogen-activated protein kinase and matrix metalloproteinase-2 expressions in human colon tumors. World J. Gastroenterology 11: 3065-3069, 2005.
- Exercise-related novel gene is involved in myoblast differentiation. Biomed. Res. 26:79-85, 2005.
- PACAP Receptor (PAC1-R) Expression in Rat and Rhesus Monkey Thymus.Annals of the New York Academy of Sciences 1070: 581-585, 2006.
- Short time exposure to hypoxia promotes H9c2 cell growth.Biochim.Biophys.Acta 1760: 1293-1297, 2006.
- Ornithine decarboxylase overexpression enhances phosphorylation of ERK and p38 and matrix metalloproteinase-2 expression. Cell Biol. Int. 31:141-147,2007.
- Long-term effects of subcutaneously injected 2,3,7,8-tetrachlorodibenzo p-dioxin on the liver of Rhesus monkeys. Chemosphere 67:399-404, 2007.
- A single-injection ornithine decarboxylase-directed antisense therapy using atelocollagen to suppress human cancer growth. Cancer 109:993-1002, 2007.
- Pro-MMP-9 is associated with poor prognosis in gastric cancer. Scandinavian J. Gastroenterology 42:1070-1072, 2007.
- Polyamine depletion induces G1 and S phase arrest in human retinoblastoma Y79 cells. Cancer Cell Int. 8:2-9, 2008.
- Mouse AKR1E1 is orthologue of pig liver NADPH dependent 1,5-anhydro-D-fructose reductase. Bioscience, Biotechnology, and Biochemistry 72: 872-876, 2008.
- Developmentally regulated expression of matrix metalloproteinases during fetal rat colon morphogenesis.
Development, Growth and Differentiation 50 (1): 41–48, 2008.
- Protective effect of captopril and enaraprilat, angiotensin-converting enzyme inhibitors, on para-nonylphenol-induced •OH generation and dopamine efflux in rat striatum. Toxicology 250: 96-99, 2008.
- In utero and lactational exposure to 2,3,7,8-tetrachloro- dibenzo-p-dioxin (TCDD) affects bone tissue in rhesus monkeys. Toxicology 253:147-52, 2008.
- Application of radical chain reactions to drug release controlling of liposomal carriers under high magnetic fields. J. Applied Physiology 105, 07B323 (2009); DOI:10.1063/1.3076894
- In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces a reduction of epididymal and ejaculated sperm number in rhesus monkeys.Reproductive Toxicology 28: 495-502, 2009.
- Inhibition of endostatin/collagen XVIII deteriorates left ventricular remodeling and heart failure in rat myocardial infarction. Circulation Journal, 74, 109-119, 2009.
- In utero and lactational exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) induces disruption of glands of the prostate and fibrosis in rhesus monkeys. Reproductive Toxicology 29:317–322, 2010.
- High dose of ascorbic acid induces cell death in mesothelioma cells. Biochem Biophys Res Commun. 394:249-253, 2010.
- EGCG induces human mesothelioma cell death by inducing reactive oxygen species and autophagy. Cancer Cell Int. 13:19-27, 2013.
- Zebularine exerts its antiproliferative activity through S phase delay and cell death in human malignant mesothelioma cells. Bioscience Biotechnology and Biochemistry 82:1-6, 2018.
- Protamine may have anti-atherogenic potential by inhibiting the binding of oxidized-low density lipoprotein to LOX-1. Bioscience Biotechnology and Biochemistry 83:1094–1101, 2019.
- Cognitive-behavioral-based physical therapy for patients with severe lumbar spinal stenosis: a report of 38 cases. Journal of Biotechnology and Bioengineering 4:19-27, 2020.
- Loss of FYCO1 leads to cataract formation. Scientific Reports 11: 13771, 2021.
|